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KMID : 0616120060370040258
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Korean Journal of Pharmacognosy
2006 Volume.37 No. 4 p.258 ~ p.265
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Hepatoprotective EFfects of Brassica rapa(Turnip) on d-Galactosamine Induced Liver Injured Rats
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Choi Hyuck-Jai
Han Myung-Joo
Baek Nam-In
Kim Dong-Hyun
Chung Hae-Gon
Kim Nam-Jae
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Abstract
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Brassica rapa L. (Turnip) which is one of the specialized crops in Ganghwa island, has been used for diuretic, digestive, and curative for jaundice, etc. In this study, the antioxidative effets and hepatoprotective effect of turnip in vitro and in vivo were investigated in order to evaluate the possibility as hepatoprotective agents. Ethanol extract of turnip potently showed the scavenging effet on DPPH and inhibitory effet on lipid peroxidation. Oral administration of turnip extract to d-galactosamine-induced experimental liver injured rats was significantly reduced the serum AST,ALT and LDH enzyme activities. And the decrease of catalase and SOD activities in liver microsomal cytosol was significantly improved by the treatment of turnip. Based on these findings, it is presumed that ethanol extract of turnip may have the hepatoprotective effect on d-galactosamine-induced hepatotoxicity rat.
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KEYWORD
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Brassica rapa, Turnip, antioxidative activity, hepatoprotective effects, transaminase activities, SOD, catalse
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